Multi-omic multi tissue monitoring of a combined lifestyle intervention in older adults (GOTO)
Presentation by Eline Slagboom, Leiden
Time: 16:00–16:45
The response of older adults to lifestyle interventions is heterogeneous and often hides beneficial effects for individuals. The personal response can be monitored by classical clinical blood based and imaging variables as well as molecular measures such as metabolomic, proteomic, transcriptomic and epigenetic profiles. These studies were performed in a 13 week combined lifestyle intervention of older adults (Growing Old Together Study, GOTO). Bioinformatics was applied to generate scores that can indicate at baseline which individuals are likely to respond well and highlight the diverse responses of men and women.